Association of HBsAg mutation patterns with hepatitis B infection outcome: Asymptomatic carriers versus HCC/cirrhotic patients
نویسندگان
چکیده
منابع مشابه
Expression Profiling of Cellular MicroRNA in Asymptomatic HBsAg Carriers and Chronic Hepatitis B Patients
BACKGROUND MicroRNAs (miRNAs) may serve as potential molecular markers to predict liver injury resulting from chronic hepatitis B (CHB). In the present study, we want to study the expression profile and clinical significance of miRNAs at different stages of CHB virus infection. METHODS Using miRNA microarray, we investigated the global expression profiles of cellular miRNA in asymptomatic hep...
متن کاملHBsAg and HBcAg in the livers of asymptomatic hepatitis B antigen carriers.
Asymptomatic blood donors with persistent HBs antigenaemia have a variety of histological lesions in the liver, and serial biopsies indicate that, in some, these lesions may progress. The immunoperoxidase technique was found to be a sensitive method for the histological demonstration of HBsAg and HBcAg. Livers showing minor histological changes contained more HBsAg than those with active lesion...
متن کاملThe Absence of Hepatitis C Virus Infection Among Patients with Hepatitis B virus in Mashhad, Iran
Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...
متن کاملCHARACTERISTICS AND PREVALENCE OF OCCULT HEPATITIS B VIRUS INFECTION IN PATIENTS WITH HEPATITIS C IN IRAN
ABSTRACT Background: Hepatitis B virus (HBV) infection in patients who lack detectable hepatitis B surface antigen (HBsAg) is called occult hepatitis B infection. Such infections have been frequently identified in patients with chronic hepatitis Cliver disease, but their prevalence is not known. Methods: 207 patients with chronic hepatitis C who were HCV -RNA and antiHCV positive were stu...
متن کاملprediction of hbsag conformational changes in iranian patients with occult hepatitis b infection with bioinformatics tools
عفونت نهفته بیماری هپاتیت b به عنوان عفونت با dna hbv قابل شناسایی و آنتیژن سطحی hbsag غیرقابل شناسایی در خون بیماران است. عقیده بر این است که شناسایی ویروس هپاتیت b به وسیله میزبان در منطقه a از آنتی ژن سطحی (hbsag) انجام میشود. اما به دلیل فقدان ساختار سه بعدی hbsag، مدرکی برای این فرضیه وجود ندارد. پیشگویی ساختار سه بعدی توالی موتان یافته و وحشی از توالی اولیه، تغییرات ساختاری را آشکار می...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Hepatology
سال: 2019
ISSN: 1665-2681
DOI: 10.1016/j.aohep.2018.12.006